The Host Genotype Actively Shapes Its Microbiome Across Generations in Laboratory Mice

By:
Laurentiu Benga, Anna Rehm, Christina Gougoula, Philipp Westhoff, Thorsten Wachtmeister, W. Peter M. Benten, Eva Engelhardt, Andreas P. M. Weber, Karl Köhrer, Martin Sager, Stefan Janssen
Date:
2024
Resource type:
Blogs/news/opinion
Link:

This research explores the influence of host genotype versus maternal legacy on microbiome composition in laboratory mice across six generations. Findings reveal that while maternal legacy influences microbiome in early generations, host genotype predominantly shapes microbiome diversity over time under controlled conditions.
credit: canva