Clinical Implications of Malnutrition in Huntington’s Disease Progression: Evidence from a Chinese Cohort and Mendelian Randomization

By:
Jie-Qiang Xia; Yang-Fan Cheng; Si-Rui Zhang; Yuan-Zheng Ma; Jia-Jia Fu; et al.
Date:
2026
Resource type:
Peer review
Link:
Clinical Implications of Malnutrition in Huntington’s Disease Progression: Evid…

This study shows that malnutrition is common in Huntington’s disease and is linked to worse functional ability and cognitive decline, though it does not independently predict survival. Genetic analysis suggests that immune-related factors, particularly lymphocyte levels, may help slow motor progression, highlighting potential immunonutrition pathways.