The article examines the relationship between vitamin D status and inflammation markers (CRP and AGP) among preschool children and nonpregnant females of reproductive age. Using cross-sectional data from six nationally representative nutrition surveys, the study finds weak and inconsistent correlations between inflammation biomarkers and serum 25(OH)D concentrations. The results suggest that adjusting for inflammation when estimating the population prevalence of vitamin D deficiency is unnecessary.
The research highlights the global prevalence of vitamin D deficiency, emphasizing the importance of accurate assessment. It also discusses the potential role of inflammation in altering vitamin D metabolism but concludes that current evidence does not support inflammation adjustment in population-level assessments.
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