A Systematic Review and Meta-Analysis of the Effect of Total Parenteral Nutrition and Enteral Nutrition on the Prognosis of Patients with Acute Pancreatitis

By:
Mingshuang Liu, Cong Gao
Date:
2021
Resource type:
Blogs/news/opinion
Link:

This systematic review and meta-analysis compare total parenteral nutrition (TPN) and enteral nutrition (TEN) in patients with acute pancreatitis, assessing their impact on prognosis and treatment outcomes.

Key findings:

TEN is associated with lower infection rates (odds ratio: 0.25, P=0.003) compared to TPN.
Mortality rates are significantly lower in patients receiving TEN (OR = 0.59, P=0.03).
Multiple organ failure rates show no significant difference between the two methods.
Hospital stay duration is shorter with TEN (mean difference = -4.18 days, P<0.001).
Despite the benefits of TEN, attention must be given to potential complications during implementation.
This study reinforces the importance of enteral nutrition as a preferred feeding method in acute pancreatitis to enhance patient outcomes.

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