Resource type:
Blogs/news/opinion
Link:
This study employs Mendelian Randomization to explore the causal relationships between BMI, circulating polyunsaturated fatty acids (PUFAs), and leukocyte telomere length (LTL). The findings reveal that higher circulating levels of linoleic acid (LA) are associated with longer LTL, suggesting a mediating role in the BMI-LTL relationship. The study integrates genetic and animal model analyses to elucidate mechanisms linking obesity, aging, and metabolic processes.
credit: canva