This study investigates the prognostic significance of the albumin-to-creatinine ratio (ACR) in solid tumor patients. The research analyzes data from the Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) dataset (2013–2022) to explore the relationship between ACR levels and overall survival (OS) in patients under 65 years old.
Key findings:
Higher ACR levels were linked to improved OS, particularly in nasopharyngeal carcinoma, gastrointestinal tumors, and urogenital neoplasms.
Low ACR was associated with poor nutritional and functional status, reflected in Patient-Generated Subjective Global Assessment (PG-SGA) scores and Karnofsky Performance Status (KPS).
Kaplan-Meier survival analysis confirmed the prognostic value of ACR, supporting its potential as a biomarker for cancer prognosis.
The study highlights ACR as a simple, accessible biomarker that could be used for predicting survival outcomes in cancer patients.
Photo Credit: GAIN