Development and Pragmatic Randomized Controlled Trial of Healthy Ketogenic Diet Versus Energy-Restricted Diet on Weight Loss in Adults with Obesity

This randomized controlled trial compared a Healthy Ketogenic Diet (HKD) to an Energy-Restricted Diet (ERD) in 80 obese adults. The HKD group achieved significantly greater weight loss and better improvements in metabolic health without increasing LDL cholesterol. The study supports HKD as an effective obesity intervention.