Breakfast Skipping and Major Depressive Disorder: Role of Gut Microbes in a Mendelian Randomization Study (2024)

This Mendelian randomization study investigates the relationship between breakfast skipping and major depressive disorder (MDD) and explores the mediating role of the gut microbiome. Results indicate a significant association between breakfast skipping and increased MDD risk, although gut microbiome analysis showed minimal evidence for a direct mediation effect. These findings underscore the potential mental health benefits of regular breakfast consumption and suggest further studies on gut-brain interactions.