Protective Effects of Sulforaphane Preventing Inflammation and Oxidative Stress to Enhance Metabolic Health: A Narrative Review

By:
Eugenia Carvalho, Elisabet Børsheim,Sharda Singh, Louise T. Dalgaard,Edilene Maria Queiroz Araújo, Inês Alves
Date:
2025
Resource type:
Peer review
Link:

This narrative review highlights the protective metabolic benefits of sulforaphane (SFN), a compound found in cruciferous vegetables. SFN acts via the Nrf2 pathway, promoting antioxidant and anti-inflammatory responses. It may reduce oxidative stress, improve mitochondrial function, and mitigate conditions like obesity, type 2 diabetes, and aging-related metabolic decline. The review also outlines safe dosing, bioavailability, and potential applications in geroscience and nutraceutical interventions. SFN’s capacity to activate endogenous antioxidant systems positions it as a promising agent for lifelong metabolic health.

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